--- title: "Mission Bay & SoMa, San Francisco — Class A submarket" description: "Tech-led southern submarket." canonical: https://classa.info/cities/san-francisco/mission-bay-soma pageType: neighborhood lastUpdated: 2026-04-15T00:00:00.000Z license: "CC BY 4.0 with attribution to Class A Atlas (https://classa.info)." --- > Mission Bay & SoMa is a prime-tier Class A submarket of San Francisco with average asking rent around $80/sqft/yr. ## TL;DR - Deepest biotech tenancy in the city. - Mission Rock delivery anchored 2024. - Strong Caltrain access. # Mission Bay & SoMa, San Francisco — Class A submarket *Tech-led southern submarket.* · Tier: prime · Avg rent: $80/sqft/yr ## TL;DR - Deepest biotech tenancy in the city. - Mission Rock delivery anchored 2024. - Strong Caltrain access. ## Overview Mission Bay and SoMa together form the city's tech and biotech corridor. Mission Rock anchors recent [Class A](/glossary/class-a) delivery; UCSF and Chase Center anchor the broader Mission Bay cluster. ## Tenant profile Biotech, technology, consumer-internet, gaming. ## Typical specification 30-50,000 sqft floor plates with lab-ready capability in select assets. ## Transit Caltrain 4th & King, Muni Metro T-Third, Central Subway. Caltrain anchor for Peninsula commuters. ## Amenities Chase Center, Crane Cove Park, Oracle Park. ## Comparable buildings - **Mission Rock** [](https://www.google.com/maps/search/?api=1&query=Mission%20Rock%2C%201100%203rd%20Street%2C%20San%20Francisco%2C%20CA%2094158%2C%20Mission%20Bay%20%26%20SoMa%2C%20San%20Francisco%2C%20United%20States&query_place_id=EikxMTAwIDNyZCBTdCwgU2FuIEZyYW5jaXNjbywgQ0EgOTQxNTgsIFVTQSIxEi8KFAoSCWkWLX7af4-AEVyWG5gZlZNCEMwIKhQKEgkhyhqOsX-PgBFAPqdps8liDw) - **100 Hooper** [](https://www.google.com/maps/search/?api=1&query=100%20Hooper%2C%20100%20Hooper%20Street%2C%20San%20Francisco%2C%20CA%2094107%2C%20Mission%20Bay%20%26%20SoMa%2C%20San%20Francisco%2C%20United%20States&query_place_id=ChIJR46XYs1_j4ARcSsGD0V7KTc) ## Where Mission Bay & SoMa sits in San Francisco Mission Bay & SoMa is one of 6 Class A submarkets we cover in San Francisco, classified as prime tier with an average asking rent around $80/sqft/yr. Compared with the broader San Francisco Class A stock, Mission Bay & SoMa typically attracts Biotech, technology, consumer-internet, gaming and competes most directly with the city's other prime submarkets on building specification, transit access, and [amenitisation](/glossary/amenitisation). Adjacent submarkets to study alongside Mission Bay & SoMa: [Transbay](/cities/san-francisco/transbay), [Financial District](/cities/san-francisco/financial-district), [Jackson Square](/cities/san-francisco/jackson-square), [Mission Bay](/cities/san-francisco/mission-bay). The full San Francisco submarket atlas is at [/cities/san-francisco](/cities/san-francisco). ## Topic deep-dives for Mission Bay & SoMa For an institutional Class A occupier evaluating Mission Bay & SoMa, the highest-leverage analyses to commission next are the rent benchmark, the concession-package comparable, and the ESG performance baseline. Class A Atlas covers each as a dedicated topic page for this submarket: - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/rents-and-availability) - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/tenant-profile) - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/transit-and-commute) - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/amenity-and-lifestyle) - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/trophy-and-comparables) - [Mission Bay & SoMa — ](/cities/san-francisco/mission-bay-soma/fit-out-and-spec) ## Related glossary Terminology specific to San Francisco Class A leasing and to the prime tier: [Class A](/glossary/class-a), [Trophy asset](/glossary/trophy-asset), [Effective rent](/glossary/effective-rent), [Concession package](/glossary/concession-package), [TI allowance](/glossary/ti-allowance), [Submarket tier](/glossary/submarket-tier). ## Editorial provenance Reviewed by [**Miriam Hollander**](/about/authors/miriam-hollander) — Lead market analyst. Last updated 2026-04-15. See our [methodology](/about/methodology) and [editorial standards](/about/editorial-standards). ### Primary sources for this page - [CBRE Marketview reports](https://www.cbre.com/insights) — CBRE - [JLL Office Insight](https://www.jll.com/en/trends-and-insights) — JLL - [Cushman & Wakefield Marketbeat](https://www.cushmanwakefield.com/en/insights) — Cushman & Wakefield - [Savills World Research](https://www.savills.com/research_articles/) — Savills - [Colliers Global Office Outlook](https://www.colliers.com/en/research) — Colliers [Full sources index](/about/sources) · [Submit a correction](/about/corrections) ## Related topics - [**Class A Lease Negotiation**](/topics/class-a-lease-negotiation) — How to negotiate a Class A office lease — the playbook from LOI to signed deal. - [**Hybrid Workplace Strategy**](/topics/hybrid-workplace-strategy) — How to size, structure, and lease a Class A office for a hybrid workforce. - [**ESG / LEED for Tenants**](/topics/esg-leed-tenants) — How tenants evaluate, negotiate, and report on ESG performance in a Class A office lease. - [**Cross-border Expansion**](/topics/cross-border-expansion) — How to run a coordinated Class A office search across multiple geographies. - [**Fit-out Capex**](/topics/fit-out-capex) — How to budget, sequence, and govern Class A office [fit-out](/topics/fit-out-capex)">fit-out capex. - [**Lease vs Flex**](/topics/lease-vs-flex) — When premium flex (coworking, [managed office](/glossary/managed-office)) beats a conventional Class A lease — and vice versa. --- Citation: Source: Class A Atlas (https://classa.info/cities/san-francisco/mission-bay-soma), updated 2026-04-15T00:00:00.000Z.