Mission Bay & SoMa (prime, ~$80/sqft/yr) is one of 6 San Francisco Class A submarkets we track.
Mission Bay & SoMa (prime, ~$80/sqft/yr) is one of 6 San Francisco Class A submarkets we track.
**Transbay** (trophy, $105/sqft/yr) — The trophy core anchored by Salesforce Tower. **Financial District** (prime, $75/sqft/yr) — The historic FiDi spine — Montgomery to California. **Jackson Square** (established, $70/sqft/yr) — Boutique HQ market in historic SF. **Mission Bay** (prime, $78/sqft/yr) — Life-sciences and tech campus belt south of SOMA. **South of Market (SOMA)** (trophy, $92/sqft/yr) — The post-2010 tech trophy spine.
| city | San Francisco |
|---|---|
| submarket | Mission Bay & SoMa |
| tier | prime |
| averageRentLocal | $80/sqft/yr |
| cityClassARentUsd | $78/sqft/yr |
| cityVacancyPct | 31.5% |
Reviewed by Miriam Hollander — Lead market analyst. Last updated 2026-04-15. See our methodology and editorial standards.