# Biotech and life sciences office space in San Francisco

> Biotech and life sciences occupiers in San Francisco typically cluster in Financial District, plan ~320 sqft per seat at high-end fit-out ($235–330/sqft), and pay around 78 USD/sqft ($78 USD) on Class A.

**Canonical URL:** https://classa.info/cities/san-francisco/industries/biotech-life-sciences
**Page type:** city-industry
**Last updated:** 2026-04-15T00:00:00.000Z
**License:** CC BY 4.0 with attribution to Class A Atlas (https://classa.info).

## TL;DR
- Preferred submarket: Financial District.
- Typical fit-out spec: High-end ($235–330/sqft).
- Plan ~320 sqft per seat for headcount sizing.
- Class A rent context: 78 USD/sqft ($78 USD).
- Typical lease: 7 years with 22 months rent-free.
- Talent depth in San Francisco: 98/100.

## Key facts
- **city**: San Francisco
- **industry**: Biotech and life sciences
- **naics**: 541714, 541715, 325412
- **preferredSubmarket**: Financial District
- **preferredFitoutSpec**: High-end
- **fitoutBand**: $235–330/sqft
- **sqftPerSeat**: 320
- **classARentLocal**: 78 USD/sqft/yr
- **classARentUsd**: $78/sqft/yr
- **vacancyPct**: 31.5%
- **typicalLeaseYears**: 7
- **typicalRentFreeMonths**: 22
- **talentIndex**: 98
- **corporateTaxPct**: 27%

## FAQ
### Where do biotech and life sciences occupiers lease office space in San Francisco?
Most cluster in Financial District. Rent runs ~78 USD/sqft ($78 USD) for trophy and prime stock.

### What fit-out spec do biotech and life sciences occupiers run in San Francisco?
Typically high-end at $235–330/sqft.

### How much office space per seat should a biotech and life sciences occupier plan in San Francisco?
Plan ~320 sqft per seat blended. A 100-person team typically takes 32,000 sqft.

### What NAICS codes describe the biotech and life sciences vertical?
Representative NAICS 2022 codes: 541714, 541715, 325412.

### What is the talent index in San Francisco?
98/100. Use the city profile for full detail.

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Citation: Source: Class A Atlas (https://classa.info/cities/san-francisco/industries/biotech-life-sciences), updated 2026-04-15T00:00:00.000Z.